PPHrisk
LiveFree clinical decision-support calculator for postpartum hemorrhage risk. Implements CMQCC V3, AWHONN, ACOG Safe Motherhood Initiative protocols. Used by L&D teams nationally.
pphrisk.com →Ravi Goyal, MD, PhD, MBA, FAHA is a physician-scientist at the University of Arizona advancing the science, devices, and software that close gaps in maternal and reproductive care — from NIH-funded discovery to clinical tools used in labor and delivery units today.
The thesis
Women's health represents roughly half the population yet a small fraction of medical device R&D, AI training data, and clinical research investment. Dr. Goyal's work spans three levels of that gap.
NIH-funded laboratory research on developmental programming, vascular biology, and epigenetic mechanisms that drive maternal disease — generating the biological understanding new products require.
Decision-support tools, validated risk scores, and protocols built directly with labor-and-delivery teams — including PPHrisk, which implements CMQCC, AWHONN, and ACOG guidelines for free.
Through Epigenuity® LLC, a 6-program pipeline spanning connected devices, molecular diagnostics, digital twins, and critical-care monitoring — built with MBA-trained discipline around regulatory and reimbursement strategy.
Women's health research
Maternal mortality in the United States is the highest among high-income nations — and rising. Postpartum hemorrhage is preventable in most cases. Preeclampsia, hypertensive disorders of pregnancy, and endometriosis still lack the diagnostic tools and disease-modifying therapies they deserve. The gap between what we know and what reaches the bedside is wide.
At the University of Arizona, Dr. Goyal's program targets that gap from both ends. The wet lab generates mechanistic understanding of how early-life exposures program adult disease; the translational work converts that understanding into tools clinicians can use today. Arizona is a fitting base — a Southwest-serving academic medical center with a large patient population reflecting the demographics of US maternal health risk and a research ecosystem (BIO5, SWEHSC, Center for Innovation in Brain Science) that supports interdisciplinary work.
The "why now" is harder to ignore: large-language models, cheap genomic sequencing, validated digital-twin frameworks, and reimbursement openness toward remote monitoring have all matured in parallel. Tools that were impractical five years ago can be built and deployed today — if the people building them combine the clinical insight, scientific rigor, and commercial discipline the problem actually requires.
Innovation pipeline
Developed through Epigenuity® LLC — Dr. Goyal's Tucson-based translational venture.
Free clinical decision-support calculator for postpartum hemorrhage risk. Implements CMQCC V3, AWHONN, ACOG Safe Motherhood Initiative protocols. Used by L&D teams nationally.
pphrisk.com →Digital-twin platform modeling endometriosis disease trajectory and personalized treatment response. Computational physiology meets machine learning for a notoriously under-modeled disease.
endotwin-w.com →Biofeedback-enabled pessary for pelvic organ prolapse — wholly-owned subsidiary of Epigenuity, spun out of the University of Arizona.
smartpessary.com →CRISPR-Cas13 molecular diagnostics platform for early detection — leveraging programmable RNA-targeting for sensitivity at the level required by clinical liquid biopsy.
ICU-class monitoring hardware addressing an unmet need in early-warning detection. Details under NDA.
Ultra-sensitive luminometer enabling new classes of low-signal assays — research instrument with translational diagnostic applications.
Clinical & academic impact
About
Dr. Goyal trained as a physician (MD), a research scientist (PhD), and a business administrator (MBA) — an unusual combination that lets him operate fluently across the discovery-to-deployment spectrum. He is a Fellow of the American Heart Association and serves as Vice Chair of Research in the Department of Obstetrics and Gynecology at the University of Arizona College of Medicine.
His research has been continuously NIH-funded for over a decade, with grants from NICHD, NIDDK, and the NIH Office of the Director totaling more than $14 million in direct awards. His work has been published in Physiological Reviews, Hypertension Research, PLoS ONE, Physiological Genomics, Reproductive Sciences, and many others.
Beyond the university, he is founder and CEO of Epigenuity® LLC, the Tucson-based parent company for a portfolio of women's-health devices and software including PPHrisk, EndoTwin-W, and four additional pipeline programs.
For the academic and clinical CV, visit ravigoyal.com. For institutional and University of Arizona–focused information, see ravigoyalarizona.com.
Connect
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